Product Data Sheet

HPB

Catalog No. A24040

main product photo

HPB is a selective histone deacetylase 6 (HDAC6) inhibitor with an IC₅₀ of 31 nM. It demonstrates over 30-fold selectivity for HDAC6 compared to HDAC1, making it a valuable tool for studying HDAC6-specific biological functions and a promising candidate for the development of targeted therapies in diseases involving HDAC6 dysregulation.

Chemical Information
Catalog NumA24040
M. Wt328.36
FormulaC18H20N2O4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.1800066-24-3
Synonyms
SMILESO=C(N(CC1=CC=C(C(NO)=O)C=C1)CCO)CC2=CC=CC=C2
Biological Activity
Description

HPB is a selective histone deacetylase 6 (HDAC6) inhibitor with an IC₅₀ of 31 nM. It demonstrates over 30-fold selectivity for HDAC6 compared to HDAC1, making it a valuable tool for studying HDAC6-specific biological functions and a promising candidate for the development of targeted therapies in diseases involving HDAC6 dysregulation.

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SHIPPING AND STORAGE
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