Product Data Sheet
MPT0B390
Catalog No. A24060
MPT0B390 is a potent arylsulfonamide-based histone deacetylase (HDAC) inhibitor that also functions as an inducer of tissue inhibitor of metalloproteinases 3 (TIMP3). It exhibits strong antitumor properties, including inhibition of tumor growth, metastasis, and angiogenesis. MPT0B390 shows significant antiproliferative activity against the human colon cancer cell line HCT116, with a GI₅₀ of 0.03 μM, highlighting its potential as a promising candidate for cancer therapy.
Chemical Information
| Catalog Num | A24060 |
|---|---|
| M. Wt | 375.40 |
| Formula | C17H17N3O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1817802-18-8 |
| Synonyms | |
| SMILES | O=C(NO)/C=C/C1=CN=C(N(S(=O)(C2=CC=C(OC)C=C2)=O)CC3)C3=C1 |
Biological Activity
| Description | MPT0B390 is a potent arylsulfonamide-based histone deacetylase (HDAC) inhibitor that also functions as an inducer of tissue inhibitor of metalloproteinases 3 (TIMP3). It exhibits strong antitumor properties, including inhibition of tumor growth, metastasis, and angiogenesis. MPT0B390 shows significant antiproliferative activity against the human colon cancer cell line HCT116, with a GI₅₀ of 0.03 μM, highlighting its potential as a promising candidate for cancer therapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
