Product Data Sheet
CM-1758
Catalog No. A24062
CM-1758 is a histone deacetylase (HDAC) inhibitor with demonstrated antitumor activity in vivo. In acute myeloid leukemia (AML) cells, CM-1758 induces the acetylation of non-histone proteins, suggesting a broader epigenetic and post-translational regulatory effect beyond chromatin remodeling. Its dual impact on tumor growth and protein acetylation supports its potential as a therapeutic agent in hematologic malignancies.
Chemical Information
| Catalog Num | A24062 |
|---|---|
| M. Wt | 532.59 |
| Formula | C28H32N6O5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2256079-39-5 |
| Synonyms | |
| SMILES | O=C(NO)C1=CN=C(N2CCC(CNC3=CC(C4=C(C)OC(C)=C4)=NC5=CC(OC)=C(OC)C=C53)CC2)N=C1 |
Biological Activity
| Description | CM-1758 is a histone deacetylase (HDAC) inhibitor with demonstrated antitumor activity in vivo. In acute myeloid leukemia (AML) cells, CM-1758 induces the acetylation of non-histone proteins, suggesting a broader epigenetic and post-translational regulatory effect beyond chromatin remodeling. Its dual impact on tumor growth and protein acetylation supports its potential as a therapeutic agent in hematologic malignancies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
