Product Data Sheet

Chemerin-9 (149-157) (TFA)

Catalog No. A24120

main product photo
Chemerin-9 (149–157) TFA is a potent peptide agonist of chemokine-like receptor 1 (CMKLR1), exhibiting significant anti-inflammatory activity. It activates downstream signaling pathways by stimulating the phosphorylation of Akt and ERK and promoting reactive oxygen species (ROS) production. Chemerin-9 (149–157) TFA has demonstrated neuroprotective effects, including the amelioration of Aβ₁₋₄₂-induced memory impairment in Alzheimer's disease models. Additionally, it plays important roles in modulating immune responses, regulating adipocyte differentiation, and improving glucose metabolism, making it a valuable tool for research in inflammation, neurodegeneration, and metabolic disorders.
Chemical Information
Catalog NumA24120
M. Wt1177.18
FormulaC56H67F3N10O15
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.nan
Synonyms
SMILES
Biological Activity
DescriptionChemerin-9 (149–157) TFA is a potent peptide agonist of chemokine-like receptor 1 (CMKLR1), exhibiting significant anti-inflammatory activity. It activates downstream signaling pathways by stimulating the phosphorylation of Akt and ERK and promoting reactive oxygen species (ROS) production. Chemerin-9 (149–157) TFA has demonstrated neuroprotective effects, including the amelioration of Aβ₁₋₄₂-induced memory impairment in Alzheimer's disease models. Additionally, it plays important roles in modulating immune responses, regulating adipocyte differentiation, and improving glucose metabolism, making it a valuable tool for research in inflammation, neurodegeneration, and metabolic disorders.
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