Product Data Sheet
PB1
Catalog No. A24231
PB1 is a potent intracellular disulfide-reducing agent, designed as a borane-protected analogue of TCEP (tris(2-carboxyethyl)phosphine). It offers several advantages, including excellent cell permeability, the ability to establish high intracellular concentration gradients, and chemical stability. PB1 promotes retinal ganglion cell survival following axotomy in vitro at nanomolar to picomolar concentrations, making it a valuable tool for neuroprotective research.
Chemical Information
| Catalog Num | A24231 |
|---|---|
| M. Wt | 296.11 |
| Formula | C14H22BO4P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 188714-28-5 |
| Synonyms | |
| SMILES | [H-][B+3]([P](CCC(OC)=O)(C1=CC=CC=C1)CCC(OC)=O)([H-])[H-] |
Biological Activity
| Description | PB1 is a potent intracellular disulfide-reducing agent, designed as a borane-protected analogue of TCEP (tris(2-carboxyethyl)phosphine). It offers several advantages, including excellent cell permeability, the ability to establish high intracellular concentration gradients, and chemical stability. PB1 promotes retinal ganglion cell survival following axotomy in vitro at nanomolar to picomolar concentrations, making it a valuable tool for neuroprotective research. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
