Product Data Sheet
AZA197
Catalog No. A24247
AZA197 is a selective small molecule inhibitor of Cdc42 that suppresses colon cancer cell proliferation, migration, and invasion, while promoting apoptosis. Its mechanism involves downregulation of the PAK1 and ERK signaling pathways. In vivo, AZA197 significantly reduces tumor growth and improves survival in SW620 xenograft mouse models, highlighting its potential for cancer research and therapy.
Chemical Information
| Catalog Num | A24247 |
|---|---|
| M. Wt | 408.58 |
| Formula | C24H36N6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1249398-09-1 |
| Synonyms | |
| SMILES | CC1=NC(NC(CCCN(CC)CC)C)=NC(NCCC2=CNC3=C2C=CC=C3)=C1 |
Biological Activity
| Description | AZA197 is a selective small molecule inhibitor of Cdc42 that suppresses colon cancer cell proliferation, migration, and invasion, while promoting apoptosis. Its mechanism involves downregulation of the PAK1 and ERK signaling pathways. In vivo, AZA197 significantly reduces tumor growth and improves survival in SW620 xenograft mouse models, highlighting its potential for cancer research and therapy. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
