Product Data Sheet

JNJ19567470

Catalog No. A24293

main product photo
JNJ19567470 (R317573) is a selective, non-peptidergic corticotropin-releasing factor type 1 (CRF₁) receptor antagonist. It effectively blocks sodium lactate (NaLac)-induced panic-like behavior and associated cardiovascular responses. JNJ19567470 also reduces regional glucose utilization in the amygdala and attenuates anxiety-related responses
Chemical Information
Catalog NumA24293
M. Wt443.38
FormulaC22H27BrN4O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.724471-26-5
SynonymsR317573; CRA5626; TAI041
SMILESBrC1=CC(C)=C(N2C=C(C)C3=C(N4CCC(CC4)CO)N=C(C)N=C32)C(C)=C1
Biological Activity
DescriptionJNJ19567470 (R317573) is a selective, non-peptidergic corticotropin-releasing factor type 1 (CRF₁) receptor antagonist. It effectively blocks sodium lactate (NaLac)-induced panic-like behavior and associated cardiovascular responses. JNJ19567470 also reduces regional glucose utilization in the amygdala and attenuates anxiety-related responses
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