Product Data Sheet
TAK-075
Catalog No. A24297
TAK-075 is an orally active and highly potent calcium-sensing receptor (CaSR) antagonist with an IC50 of 0.94 nM. It promotes transient parathyroid hormone (PTH) secretion in rats and effectively prevents the sustained suppression of PTH caused by the buildup of active metabolites, thereby preserving normal PTH secretion dynamics. TAK-075 is a valuable compound for research in metabolic bone diseases, including osteoporosis.
Chemical Information
| Catalog Num | A24297 |
|---|---|
| M. Wt | 630.84 |
| Formula | C36H46N4O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 667931-33-1 |
| Synonyms | |
| SMILES | O=S(O)(C1=CC=C(C=C1)C)=O.CCC(CC)(C2=CC=C(C=C2)CC)NC(C3=C4N(N=C3C)C(C)(C[C@H](C5=CC=CC=C5)N4)C)=O |
Biological Activity
| Description | TAK-075 is an orally active and highly potent calcium-sensing receptor (CaSR) antagonist with an IC50 of 0.94 nM. It promotes transient parathyroid hormone (PTH) secretion in rats and effectively prevents the sustained suppression of PTH caused by the buildup of active metabolites, thereby preserving normal PTH secretion dynamics. TAK-075 is a valuable compound for research in metabolic bone diseases, including osteoporosis. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
