Product Data Sheet

Calindol hydrochloride

Catalog No. A24304

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Calindol hydrochloride is a positive allosteric modulator (PAM) of the calcium-sensing receptor (CaSR), acting as a calcimimetic compound. It enhances CaSR activation with an EC50 of 132 nM, making it a valuable tool for studying calcium homeostasis and related signaling pathways.
Chemical Information
Catalog NumA24304
M. Wt336.86
FormulaC21H21ClN2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.729610-18-8
Synonyms
SMILESC[C@@H](NCC1=CC2=CC=CC=C2N1)C3=C4C=CC=CC4=CC=C3.Cl
Biological Activity
DescriptionCalindol hydrochloride is a positive allosteric modulator (PAM) of the calcium-sensing receptor (CaSR), acting as a calcimimetic compound. It enhances CaSR activation with an EC50 of 132 nM, making it a valuable tool for studying calcium homeostasis and related signaling pathways.
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