Product Data Sheet
Pulrodemstat benzenesulfonate
Catalog No. A24339
Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent, selective, reversible, and orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC₅₀ of 0.25 nM. It exhibits significantly lower inhibitory activity against related enzymes such as LSD2, MAO-A, and MAO-B. CC-90011 induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells and demonstrates strong anticancer activity, making it a promising candidate for epigenetic cancer therapy.
Chemical Information
| Catalog Num | A24339 |
|---|---|
| M. Wt | 609.64 |
| Formula | C30H29F2N5O5S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2097523-60-7 |
| Synonyms | CC-90011 benzenesulfonate; LSD1-IN-7 benzenesulfonate |
| SMILES | N#CC1=CC=C(C(N=C(N2CCC(N)CC2)N3C)=C(C4=CC=C(OC)C(F)=C4)C3=O)C=C1F.O=S(C5=CC=CC=C5)(O)=O |
Biological Activity
| Description | Pulrodemstat benzenesulfonate (CC-90011 benzenesulfonate) is a potent, selective, reversible, and orally active inhibitor of lysine-specific demethylase 1 (LSD1), with an IC₅₀ of 0.25 nM. It exhibits significantly lower inhibitory activity against related enzymes such as LSD2, MAO-A, and MAO-B. CC-90011 induces differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cells and demonstrates strong anticancer activity, making it a promising candidate for epigenetic cancer therapy. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
