Product Data Sheet

DC-05

Catalog No. A24344

main product photo
DC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor with an IC₅₀ of 10.3 μM and a binding affinity (K\_d) of 1.09 μM. It interferes with DNMT1-mediated DNA methylation, making it a useful compound for studying epigenetic regulation and exploring potential therapeutic applications in diseases involving aberrant DNA methylation.
Chemical Information
Catalog NumA24344
M. Wt383.49
FormulaC25H25N3O
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.890643-16-0
Synonyms
SMILESOC(CNCCC1=CNC2=C1C=CC=C2)CN(C3=CC=CC=C34)C5=C4C=CC=C5
Biological Activity
DescriptionDC-05 is a DNA methyltransferase 1 (DNMT1) inhibitor with an IC₅₀ of 10.3 μM and a binding affinity (K\_d) of 1.09 μM. It interferes with DNMT1-mediated DNA methylation, making it a useful compound for studying epigenetic regulation and exploring potential therapeutic applications in diseases involving aberrant DNA methylation.
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