Product Data Sheet
GNE-886
Catalog No. A24412
GNE-886 (Compound 21) is a potent and selective inhibitor of the CECR2 bromodomain (BRD), with an IC₅₀ of 0.016 µM and an EC₅₀ of 370 nM. It also exhibits inhibitory activity against BRD9, with an IC₅₀ of 1.6 µM.
Chemical Information
| Catalog Num | A24412 |
|---|---|
| M. Wt | 498.58 |
| Formula | C28H30N6O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2101957-05-3 |
| Synonyms | |
| SMILES | O=C(C1=CN(CC=C)C(C2=C1C=CN2)=O)N(C3CCN(C4=NC=NC(C5=CC=CC(OC)=C5)=C4)CC3)C |
Biological Activity
| Description | GNE-886 (Compound 21) is a potent and selective inhibitor of the CECR2 bromodomain (BRD), with an IC₅₀ of 0.016 µM and an EC₅₀ of 370 nM. It also exhibits inhibitory activity against BRD9, with an IC₅₀ of 1.6 µM. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
