Product Data Sheet
ER-Tracker Green
Catalog No. A24506
ER-Tracker dye is a BODIPY-based fluorescent probe conjugated with Glibenclamide, exhibiting high selectivity for the endoplasmic reticulum (ER). It is cell-permeable, non-toxic at low concentrations, and retains partial fluorescence after formaldehyde fixation. As an environment-sensitive dye, R-Tracker offers a long fluorescence lifetime and a high extinction coefficient. Glibenclamide, an ATP-sensitive K⁺ channel (Kir6.x, KATP) and CFTR Cl⁻ channel blocker, mediates ER targeting. R-Tracker is not suitable for post-fixation staining.
Chemical Information
| Catalog Num | A24506 |
|---|---|
| M. Wt | 783.09 |
| Formula | C37H42BClF2N6O6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 730931-46-1 |
| Synonyms | |
| SMILES | O=C(NS(=O)(C1=CC=C(CCNC(C2=C(OC)C(NC(CCC3=CC=C4C=C5C(C)=CC(C)=[N]5[B+3]([F-])([N-]43)[F-])=O)=CC(Cl)=C2)=O)C=C1)=O)NC6CCCCC6 |
Biological Activity
| Description | ER-Tracker dye is a BODIPY-based fluorescent probe conjugated with Glibenclamide, exhibiting high selectivity for the endoplasmic reticulum (ER). It is cell-permeable, non-toxic at low concentrations, and retains partial fluorescence after formaldehyde fixation. As an environment-sensitive dye, R-Tracker offers a long fluorescence lifetime and a high extinction coefficient. Glibenclamide, an ATP-sensitive K⁺ channel (Kir6.x, KATP) and CFTR Cl⁻ channel blocker, mediates ER targeting. R-Tracker is not suitable for post-fixation staining. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
