Product Data Sheet

Ibetazol

Catalog No. A24520

main product photo
Ibetazol is an importin β1 (KPNB1) inhibitor that covalently binds to Cys585 of importin β1, thereby blocking importin β1-mediated nuclear import. It exhibits an EC₅₀ of 6.1 µM in cellular assays.
Chemical Information
Catalog NumA24520
M. Wt300.30
FormulaC13H11F3N2OS
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.nan
Synonyms
SMILESFC(F)(F)C1=CC(C2=CC=CC=C2)=NC(S(CC)=O)=N1
Biological Activity
DescriptionIbetazol is an importin β1 (KPNB1) inhibitor that covalently binds to Cys585 of importin β1, thereby blocking importin β1-mediated nuclear import. It exhibits an EC₅₀ of 6.1 µM in cellular assays.
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SHIPPING AND STORAGE
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