Product Data Sheet

LCKLSL

Catalog No. A24552

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LCKLSL is an N-terminal hexapeptide that functions as a competitive inhibitor of annexin A2 (AnxA2). It effectively blocks the interaction between tissue plasminogen activator (tPA) and AnxA2, thereby inhibiting plasmin generation. Through suppression of the tPA–AnxA2–plasmin pathway, LCKLSL exhibits significant anti-angiogenic activity and may serve as a valuable tool for studying AnxA2-mediated fibrinolytic and vascular processes.
Chemical Information
Catalog NumA24552
M. Wt675.88
FormulaC30H57N7O8S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.533902-29-3
Synonyms
SMILES
Biological Activity
DescriptionLCKLSL is an N-terminal hexapeptide that functions as a competitive inhibitor of annexin A2 (AnxA2). It effectively blocks the interaction between tissue plasminogen activator (tPA) and AnxA2, thereby inhibiting plasmin generation. Through suppression of the tPA–AnxA2–plasmin pathway, LCKLSL exhibits significant anti-angiogenic activity and may serve as a valuable tool for studying AnxA2-mediated fibrinolytic and vascular processes.
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