Product Data Sheet
A2ti-1
Catalog No. A24553
A2ti-1 is a selective, high-affinity inhibitor of the annexin A2/S100A10 heterotetramer (A2t), exhibiting an IC₅₀ of 24 μM. It specifically disrupts the protein–protein interaction (PPI) between annexin A2 and S100A10, thereby interfering with the functional assembly of the A2t complex. Through this mechanism, A2ti-1 effectively prevents infection by human papillomavirus type 16 (HPV16), highlighting its potential as a molecular tool for studying A2t-mediated viral entry and related cellular processes.
Chemical Information
| Catalog Num | A24553 |
|---|---|
| M. Wt | 382.48 |
| Formula | C20H22N4O2S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 570390-00-0 |
| Synonyms | |
| SMILES | O=C(N)CSC1=NN=C(COC2=CC=CC=C2C)N1C3=CC=CC=C3CC |
Biological Activity
| Description | A2ti-1 is a selective, high-affinity inhibitor of the annexin A2/S100A10 heterotetramer (A2t), exhibiting an IC₅₀ of 24 μM. It specifically disrupts the protein–protein interaction (PPI) between annexin A2 and S100A10, thereby interfering with the functional assembly of the A2t complex. Through this mechanism, A2ti-1 effectively prevents infection by human papillomavirus type 16 (HPV16), highlighting its potential as a molecular tool for studying A2t-mediated viral entry and related cellular processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
