Product Data Sheet

Herboxidiene

Catalog No. A24590

main product photo
Herboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome.
Chemical Information
Catalog NumA24590
M. Wt438.60
FormulaC25H42O6
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.142861-00-5
SynonymsGEX1A
SMILESC[C@H]([C@H]([C@H](O)C)OC)[C@@]1([H])O[C@]1(C)C[C@@H](/C=C/C=C(C)/[C@H]2O[C@@H](CC(O)=O)CC[C@@H]2C)C
Biological Activity
DescriptionHerboxidiene (GEX1A) is a potent phytotoxic polyketide from Streptomyces sp. A7847 with a diverse range of activities, including herbicidal, anti-cholesterol, anti-tumor effects. Herboxidiene inhibits the pre-mRNA splicing process by binding to spliceosome-associated protein (SAP) 155, a subunit of SF3b, in the splicesome.
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SHIPPING AND STORAGE
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