Product Data Sheet

STM2120

Catalog No. A24669

main product photo
STM2120 is a selective inhibitor of the METTL3-METTL14 complex, exhibiting an IC50 of 64.5 μM. This compound disrupts the methyltransferase activity of METTL3, impacting RNA methylation processes. STM2120 is valuable for investigating the roles of RNA modifications in cellular functions and disease mechanisms, particularly in cancer research.
Chemical Information
Catalog NumA24669
M. Wt333.34
FormulaC18H15N5O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2762286-04-2
Synonyms
SMILESO=C1C=C(C(NCC2=CN3C(C)=CC=CC3=N2)=O)N=C4C=CC=CN14
Biological Activity
DescriptionSTM2120 is a selective inhibitor of the METTL3-METTL14 complex, exhibiting an IC50 of 64.5 μM. This compound disrupts the methyltransferase activity of METTL3, impacting RNA methylation processes. STM2120 is valuable for investigating the roles of RNA modifications in cellular functions and disease mechanisms, particularly in cancer research.
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SHIPPING AND STORAGE
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