Product Data Sheet
RSS0680
Catalog No. A24728
RSS0680 is a small noncoding RNA (sRNA) that targets the ribosome binding site (RBS) of mRNA, functioning as a PROTAC to facilitate the degradation of various protein kinases. By competitively binding to the RBS through its conserved anti-Shine-Dalgarno sequence, RSS0680 inhibits the translation initiation of target genes. Key biological activities include the degradation of kinases such as AAK1, CDK1, and MAPK6, making it a valuable tool for investigating diseases associated with dysregulated kinase activity. Additionally, RSS0680 plays a role in bacterial oxidative stress defense and can enhance resistance to heat shock and oxidative damage by modulating metabolic pathways.
Chemical Information
| Catalog Num | A24728 |
|---|---|
| M. Wt | 1021.32 |
| Formula | C52H64N10O6S3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2769753-48-0 |
| Synonyms | |
| SMILES | CS(NC1=CC=CC(C2=CSC3=CN=C(N=C23)NC4=CC=C(N5CCN(CC5)CCCCCC(N[C@@H](C(C)(C)C)C(N6[C@@H](C[C@H](C6)O)C(N[C@H](C7=CC=C(C8=C(N=CS8)C)C=C7)C)=O)=O)=O)C=C4)=C1)(=O)=O |
Biological Activity
| Description | RSS0680 is a small noncoding RNA (sRNA) that targets the ribosome binding site (RBS) of mRNA, functioning as a PROTAC to facilitate the degradation of various protein kinases. By competitively binding to the RBS through its conserved anti-Shine-Dalgarno sequence, RSS0680 inhibits the translation initiation of target genes. Key biological activities include the degradation of kinases such as AAK1, CDK1, and MAPK6, making it a valuable tool for investigating diseases associated with dysregulated kinase activity. Additionally, RSS0680 plays a role in bacterial oxidative stress defense and can enhance resistance to heat shock and oxidative damage by modulating metabolic pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
