Product Data Sheet
ARN22089
Catalog No. A24802
ARN22089 is a novel trisubstituted pyrimidine that acts as an anticancer agent by inhibiting the interaction of CDC42 GTPases with downstream effectors. This mechanism disrupts critical signaling pathways involved in tumorigenesis. In preclinical studies, ARN22089 has demonstrated the ability to inhibit tumor growth in a BRAF mutant mouse melanoma model, making it a valuable compound for research in cancer therapeutics and signaling pathways.
Chemical Information
| Catalog Num | A24802 |
|---|---|
| M. Wt | 373.49 |
| Formula | C23H27N5 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2248691-29-2 |
| Synonyms | ARN 22089 |
| SMILES | CN(C)C1=CC(NC2=CC(C3=CC=CC=C3)=NC(C4CCNCC4)=N2)=CC=C1 |
Biological Activity
| Description | ARN22089 is a novel trisubstituted pyrimidine that acts as an anticancer agent by inhibiting the interaction of CDC42 GTPases with downstream effectors. This mechanism disrupts critical signaling pathways involved in tumorigenesis. In preclinical studies, ARN22089 has demonstrated the ability to inhibit tumor growth in a BRAF mutant mouse melanoma model, making it a valuable compound for research in cancer therapeutics and signaling pathways. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
