Product Data Sheet
Thiazole orange dimer YOYO 1
Catalog No. A24873
Thiazole orange dimer YOYO 1 is a fluorescent dye that specifically targets DNA for staining applications. As a tetracationic homodimer of oxazole yellow, it exhibits minimal fluorescence in solution but significantly enhances its emission upon binding to double-stranded DNA via diintercalation, resulting in a fluorescence intensity increase of over 3200-fold. This remarkable amplification of fluorescence makes YOYO 1 an invaluable tool for various research applications, including nucleic acid quantification and visualization in molecular biology and genetic studies.
Chemical Information
| Catalog Num | A24873 |
|---|---|
| M. Wt | 1270.64 |
| Formula | C49H58I4N6O2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 143413-85-8 |
| Synonyms | YOYO 1; YOYO1 |
| SMILES | CN1C2=CC=CC=C2O/C1=C\C3=CC=[N+](C4=C3C=CC=C4)CCC[N+](CCC[N+](CCC[N+]5=CC=C(C6=C5C=CC=C6)/C=C7N(C8=C(O/7)C=CC=C8)C)(C)C)(C)C.[I-].[I-].[I-].[I-] |
Biological Activity
| Description | Thiazole orange dimer YOYO 1 is a fluorescent dye that specifically targets DNA for staining applications. As a tetracationic homodimer of oxazole yellow, it exhibits minimal fluorescence in solution but significantly enhances its emission upon binding to double-stranded DNA via diintercalation, resulting in a fluorescence intensity increase of over 3200-fold. This remarkable amplification of fluorescence makes YOYO 1 an invaluable tool for various research applications, including nucleic acid quantification and visualization in molecular biology and genetic studies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
