Product Data Sheet
MitoPerOx
Catalog No. A24901
MitoPerOx is a fluorescent probe designed to detect lipid peroxidation specifically in mitochondria, utilizing BODIPY581/591 fluorophores. With its triphenylphosphine cation (TPP+), MitoPerOx selectively accumulates in mitochondria based on membrane potential, allowing for sensitive measurement of lipid peroxides within the inner mitochondrial membrane. The probe exhibits a ratiometric emission shift from 590 nm to 520 nm upon oxidation, facilitating accurate detection at an excitation wavelength of 488 nm. MitoPerOx is valuable for investigating oxidative stress-associated diseases, including aging, neurodegenerative disorders, and mitochondrial dysfunction.
Chemical Information
| Catalog Num | A24901 |
|---|---|
| M. Wt | 760.46 |
| Formula | C42H38BBrF2N3OP |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1392820-50-6 |
| Synonyms | |
| SMILES | O=C(CCC1=CC=C2[N-]1[B+3]([F-])([N]3=C(C=CC3=C2)/C=C/C=C/C4=CC=CC=C4)[F-])NCC[P+](C5=CC=CC=C5)(C6=CC=CC=C6)C7=CC=CC=C7.[Br-] |
Biological Activity
| Description | MitoPerOx is a fluorescent probe designed to detect lipid peroxidation specifically in mitochondria, utilizing BODIPY581/591 fluorophores. With its triphenylphosphine cation (TPP+), MitoPerOx selectively accumulates in mitochondria based on membrane potential, allowing for sensitive measurement of lipid peroxides within the inner mitochondrial membrane. The probe exhibits a ratiometric emission shift from 590 nm to 520 nm upon oxidation, facilitating accurate detection at an excitation wavelength of 488 nm. MitoPerOx is valuable for investigating oxidative stress-associated diseases, including aging, neurodegenerative disorders, and mitochondrial dysfunction. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
