Product Data Sheet

CSLP37

Catalog No. A25050

main product photo
CSLP37 is a selective inhibitor of receptor-interacting protein kinase 2 (RIPK2), exhibiting an IC50 of 16.3 nM. This compound effectively suppresses cellular responses mediated by NOD1 and NOD2, while showing no significant inhibitory activity against RIPK1 and RIPK3. CSLP37 is a valuable tool for research into inflammatory signaling pathways and the role of RIPK2 in various diseases.
Chemical Information
Catalog NumA25050
M. Wt499.60
FormulaC25H30FN5O3S
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2244984-64-1
Synonyms
SMILESCCCS(=O)(NC1=CC(C2=CC(C3=CC=C(N4CCNCC4)C=C3)=CN=C2N)=CC(F)=C1OC)=O
Biological Activity
DescriptionCSLP37 is a selective inhibitor of receptor-interacting protein kinase 2 (RIPK2), exhibiting an IC50 of 16.3 nM. This compound effectively suppresses cellular responses mediated by NOD1 and NOD2, while showing no significant inhibitory activity against RIPK1 and RIPK3. CSLP37 is a valuable tool for research into inflammatory signaling pathways and the role of RIPK2 in various diseases.
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