Product Data Sheet
Periplanetasin-4
Catalog No. A25139
Periplanetasin-4 is an antimicrobial peptide derived from the American cockroach (Periplaneta americana) that targets microbial pathogens. This peptide exhibits significant biological activities, including the reduction of cell rounding and apoptosis, while also inhibiting Clostridium difficile toxin A-induced reactive oxygen species (ROS) production. Periplanetasin-4 enhances mitochondrial calcium levels and mitigates vacuolar dysfunction in Candida albicans, highlighting its potential in antifungal research. Additionally, it demonstrates protective effects against toxin A-induced mucosal damage in mouse models, making it a valuable reagent for studies on colitis and intestinal health.
Chemical Information
| Catalog Num | A25139 |
|---|---|
| M. Wt | 1503.81 |
| Formula | C70H110N20O15S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2206807-06-7 |
| Synonyms | |
| SMILES |
Biological Activity
| Description | Periplanetasin-4 is an antimicrobial peptide derived from the American cockroach (Periplaneta americana) that targets microbial pathogens. This peptide exhibits significant biological activities, including the reduction of cell rounding and apoptosis, while also inhibiting Clostridium difficile toxin A-induced reactive oxygen species (ROS) production. Periplanetasin-4 enhances mitochondrial calcium levels and mitigates vacuolar dysfunction in Candida albicans, highlighting its potential in antifungal research. Additionally, it demonstrates protective effects against toxin A-induced mucosal damage in mouse models, making it a valuable reagent for studies on colitis and intestinal health. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
