Product Data Sheet
2'-Deoxyadenosine-15N1
Catalog No. A25152
2'-Deoxyadenosine-15N1 is a stable isotope-labeled variant of 2'-Deoxyadenosine, primarily utilized in metabolic labeling studies. It exerts a biological effect by inhibiting glucose-stimulated insulin release and impeding cAMP accumulation in pancreatic islets. Additionally, 2'-Deoxyadenosine-15N1 activates caspase-3, promoting apoptosis, and inhibits the enzyme S-adenosyl-L-homocysteine hydrolase (SAHH). Its cell growth inhibition properties suggest potential applications in cancer research, particularly in studying its effects on colon cancer cell lines.
Chemical Information
| Catalog Num | A25152 |
|---|---|
| M. Wt | 252.24 |
| Formula | C10H13N415NO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 106568-85-8 |
| Synonyms | |
| SMILES | O[C@H]1C[C@@H](O[C@@H]1CO)N2C3=C(N=C2)C([15NH2])=NC=N3 |
Biological Activity
| Description | 2'-Deoxyadenosine-15N1 is a stable isotope-labeled variant of 2'-Deoxyadenosine, primarily utilized in metabolic labeling studies. It exerts a biological effect by inhibiting glucose-stimulated insulin release and impeding cAMP accumulation in pancreatic islets. Additionally, 2'-Deoxyadenosine-15N1 activates caspase-3, promoting apoptosis, and inhibits the enzyme S-adenosyl-L-homocysteine hydrolase (SAHH). Its cell growth inhibition properties suggest potential applications in cancer research, particularly in studying its effects on colon cancer cell lines. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
