Product Data Sheet
2'-Deoxyadenosine-13C10,15N5
Catalog No. A25205
2'-Deoxyadenosine-13C10,15N5 is a stable isotope-labeled form of 2'-Deoxyadenosine that features 13C and 15N isotopes. This nucleoside is known to inhibit glucose-stimulated insulin release and attenuates increases in cyclic AMP (cAMP) accumulation in islet cells. Additionally, 2'-Deoxyadenosine activates caspase-3, promoting apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. This compound also exhibits growth inhibitory effects on various cell types and demonstrates anticancer activity against colon cancer, making it a valuable tool for biochemical and pharmaceutical research.
Chemical Information
| Catalog Num | A25205 |
|---|---|
| M. Wt | 266.14 |
| Formula | 13C10H1315N5O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1987883-24-8 |
| Synonyms | |
| SMILES | [15NH2][13C]1=[15N][13CH]=[15N][13C]2=[13C]1[15N]=[13CH][15N]2[13C@H]3[13CH]([H])[13C@H](O)[13C@@H]([13CH2]O)O3 |
Biological Activity
| Description | 2'-Deoxyadenosine-13C10,15N5 is a stable isotope-labeled form of 2'-Deoxyadenosine that features 13C and 15N isotopes. This nucleoside is known to inhibit glucose-stimulated insulin release and attenuates increases in cyclic AMP (cAMP) accumulation in islet cells. Additionally, 2'-Deoxyadenosine activates caspase-3, promoting apoptosis, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity. This compound also exhibits growth inhibitory effects on various cell types and demonstrates anticancer activity against colon cancer, making it a valuable tool for biochemical and pharmaceutical research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
