Product Data Sheet
RIPK1-IN-13
Catalog No. A25245
RIPK1-IN-13 is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1), exhibiting an IC50 value of 1139 nM. By inhibiting RIPK1, this compound effectively disrupts the necroptosis pathway, making it a valuable tool for investigating the molecular mechanisms underlying inflammatory diseases. Its applications extend to various research areas focused on cell death and inflammatory processes.
Chemical Information
| Catalog Num | A25245 |
|---|---|
| M. Wt | 397.85 |
| Formula | C21H20ClN3O3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1574547-67-3 |
| Synonyms | |
| SMILES | O=C(N1CCC2(NC(N(C2=O)CC3=CC(Cl)=CC=C3)=O)CC1)C4=CC=CC=C4 |
Biological Activity
| Description | RIPK1-IN-13 is a potent inhibitor of receptor-interacting protein kinase 1 (RIPK1), exhibiting an IC50 value of 1139 nM. By inhibiting RIPK1, this compound effectively disrupts the necroptosis pathway, making it a valuable tool for investigating the molecular mechanisms underlying inflammatory diseases. Its applications extend to various research areas focused on cell death and inflammatory processes. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
