Product Data Sheet

RIPK1-IN-9

Catalog No. A25251

main product photo
RIPK1-IN-9 is a selective inhibitor of receptor-interacting serine/threonine-protein kinase 1 (RIPK1). It demonstrates potent inhibitory activity in U937 cells with an IC50 of 2 nM, and in L929 cells with an IC50 of 1.3 nM. This compound is valuable for research in cell death, inflammation, and various diseases where RIPK1 is implicated.
Chemical Information
Catalog NumA25251
M. Wt472.51
FormulaC26H25FN6O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2682889-57-0
Synonyms
SMILESO=C1C2=C(N=CC(C3=CC4=NC(N)=NN4C=C3)=C2)CCN1CC5=CC(F)=CC=C5OC6CCCC6
Biological Activity
DescriptionRIPK1-IN-9 is a selective inhibitor of receptor-interacting serine/threonine-protein kinase 1 (RIPK1). It demonstrates potent inhibitory activity in U937 cells with an IC50 of 2 nM, and in L929 cells with an IC50 of 1.3 nM. This compound is valuable for research in cell death, inflammation, and various diseases where RIPK1 is implicated.
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