Product Data Sheet
cRIPGBM
Catalog No. A25257
cRIPGBM is a proapoptotic derivative of RIPGBM that selectively induces apoptosis in glioblastoma (GBM) cancer stem cells by targeting receptor-interacting protein kinase 2 (RIPK2). It demonstrates an EC50 of 68 nM in GBM-1 cells, making it a valuable tool for studying apoptosis mechanisms in cancer research. This compound has potential applications in investigating therapeutic strategies for GBM by promoting cell death in cancer stem cell populations.
Chemical Information
| Catalog Num | A25257 |
|---|---|
| M. Wt | 411.45 |
| Formula | C26H20FN2O2+ |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2361988-76-1 |
| Synonyms | |
| SMILES | O=C(C1=C2[N+](CC3=CC=C(F)C=C3)=C(C)N1CC4=CC=CC=C4)C5=C(C=CC=C5)C2=O |
Biological Activity
| Description | cRIPGBM is a proapoptotic derivative of RIPGBM that selectively induces apoptosis in glioblastoma (GBM) cancer stem cells by targeting receptor-interacting protein kinase 2 (RIPK2). It demonstrates an EC50 of 68 nM in GBM-1 cells, making it a valuable tool for studying apoptosis mechanisms in cancer research. This compound has potential applications in investigating therapeutic strategies for GBM by promoting cell death in cancer stem cell populations. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
