Product Data Sheet
2'-Deoxyadenosine monohydrate-5′-13C
Catalog No. A25355
2'-Deoxyadenosine monohydrate-5′-13C is a stable isotope-labeled form of 2'-Deoxyadenosine monohydrate, primarily targeting cellular metabolism and signaling pathways. This compound inhibits glucose-stimulated insulin release by blocking the increase of cyclic AMP (cAMP) in pancreatic islets and activating caspase-3, thereby promoting apoptosis. Additionally, it inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity and demonstrates growth-inhibitory effects on various cell types, exhibiting potential anticancer properties, particularly against colon cancer. These characteristics make it a valuable tool for studies in metabolic regulation and cancer research.
Chemical Information
| Catalog Num | A25355 |
|---|---|
| M. Wt | 270.25 |
| Formula | C913CH15N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 478510-77-9 |
| Synonyms | |
| SMILES | NC1=NC=NC2=C1N=CN2[C@@H]3O[C@H]([13CH2]O)[C@@H](O)C3.O |
Biological Activity
| Description | 2'-Deoxyadenosine monohydrate-5′-13C is a stable isotope-labeled form of 2'-Deoxyadenosine monohydrate, primarily targeting cellular metabolism and signaling pathways. This compound inhibits glucose-stimulated insulin release by blocking the increase of cyclic AMP (cAMP) in pancreatic islets and activating caspase-3, thereby promoting apoptosis. Additionally, it inhibits S-adenosyl-L-homocysteine hydrolase (SAHH) activity and demonstrates growth-inhibitory effects on various cell types, exhibiting potential anticancer properties, particularly against colon cancer. These characteristics make it a valuable tool for studies in metabolic regulation and cancer research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
