Product Data Sheet
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate
Catalog No. A25366
2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate is a stable isotope-labeled variant of 2'-Deoxyadenosine monohydrate, incorporating both carbon-13 and nitrogen-15. This nucleoside is known to inhibit glucose-stimulated insulin release by affecting islet cyclic AMP (cAMP) levels. Additionally, it activates caspase-3, promoting apoptosis, and demonstrates inhibition of S-adenosyl-L-homocysteine hydrolase (SAHH). Research applications include studying cellular growth inhibition and evaluating anticancer effects, particularly in colon cancer models.
Chemical Information
| Catalog Num | A25366 |
|---|---|
| M. Wt | 284.15 |
| Formula | 13C10H1515N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2483830-27-7 |
| Synonyms | |
| SMILES | [15NH2][13C]1=[15N][13CH]=[15N][13C]2=[13C]1[15N]=[13CH][15N]2[13C@H]3[13CH2][13C@H](O)[13C@@H]([13CH2]O)O3.O |
Biological Activity
| Description | 2'-Deoxyadenosine monohydrate-13C10,15N5 hydrate is a stable isotope-labeled variant of 2'-Deoxyadenosine monohydrate, incorporating both carbon-13 and nitrogen-15. This nucleoside is known to inhibit glucose-stimulated insulin release by affecting islet cyclic AMP (cAMP) levels. Additionally, it activates caspase-3, promoting apoptosis, and demonstrates inhibition of S-adenosyl-L-homocysteine hydrolase (SAHH). Research applications include studying cellular growth inhibition and evaluating anticancer effects, particularly in colon cancer models. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
