Product Data Sheet

N-3-oxo-dodecanoyl-L-homoserine lactone

Catalog No. A25378

main product photo
N-3-oxo-dodecanoyl-L-homoserine lactone is a bacterial quorum-sensing signaling molecule primarily associated with Pseudomonas aeruginosa and Burkholderia cepacia complex. This compound plays a critical role in bacterial communication, regulating gene expression in response to changes in cell density. Additionally, N-3-oxo-dodecanoyl-L-homoserine lactone has been shown to induce interleukin-8 (IL-8) production in human bronchial epithelial cells, making it valuable for research in host-pathogen interactions and inflammatory responses.
Chemical Information
Catalog NumA25378
M. Wt297.39
FormulaC16H27NO4
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.168982-69-2
SynonymsOdDHL
SMILESCCCCCCCCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O
Biological Activity
DescriptionN-3-oxo-dodecanoyl-L-homoserine lactone is a bacterial quorum-sensing signaling molecule primarily associated with Pseudomonas aeruginosa and Burkholderia cepacia complex. This compound plays a critical role in bacterial communication, regulating gene expression in response to changes in cell density. Additionally, N-3-oxo-dodecanoyl-L-homoserine lactone has been shown to induce interleukin-8 (IL-8) production in human bronchial epithelial cells, making it valuable for research in host-pathogen interactions and inflammatory responses.
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