Product Data Sheet

Oxidopamine hydrochloride

Catalog No. A25379

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Oxidopamine hydrochloride is a neurotoxin that selectively targets and destroys dopaminergic neurons by acting as a dopamine antagonist. This compound induces COX-2 activation, resulting in the synthesis of prostaglandin E2 and the secretion of pro-inflammatory cytokine IL-1β. Oxidopamine hydrochloride is primarily employed in research related to neurodegenerative disorders such as Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome.
Chemical Information
Catalog NumA25379
M. Wt205.64
FormulaC8H12ClNO3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.28094-15-7
Synonyms6-Hydroxydopamine Hydrochloride
SMILESOC1=CC(CCN)=C(O)C=C1O.[H]Cl
Biological Activity
DescriptionOxidopamine hydrochloride is a neurotoxin that selectively targets and destroys dopaminergic neurons by acting as a dopamine antagonist. This compound induces COX-2 activation, resulting in the synthesis of prostaglandin E2 and the secretion of pro-inflammatory cytokine IL-1β. Oxidopamine hydrochloride is primarily employed in research related to neurodegenerative disorders such as Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome.
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SHIPPING AND STORAGE
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