Oxidopamine hydrochloride
Catalog No. A25379

Oxidopamine hydrochloride is a neurotoxin that selectively targets and destroys dopaminergic neurons by acting as a dopamine antagonist. This compound induces COX-2 activation, resulting in the synthesis of prostaglandin E2 and the secretion of pro-inflammatory cytokine IL-1β. Oxidopamine hydrochloride is primarily employed in research related to neurodegenerative disorders such as Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome.
Chemical Information
| Catalog Num | A25379 |
|---|---|
| M. Wt | 205.64 |
| Formula | C8H12ClNO3 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 28094-15-7 |
| Synonyms | 6-Hydroxydopamine Hydrochloride |
| SMILES | OC1=CC(CCN)=C(O)C=C1O.[H]Cl |
Biological Activity
| Description | Oxidopamine hydrochloride is a neurotoxin that selectively targets and destroys dopaminergic neurons by acting as a dopamine antagonist. This compound induces COX-2 activation, resulting in the synthesis of prostaglandin E2 and the secretion of pro-inflammatory cytokine IL-1β. Oxidopamine hydrochloride is primarily employed in research related to neurodegenerative disorders such as Parkinson's disease, attention-deficit hyperactivity disorder, and Lesch-Nyhan syndrome. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


