Gomisin N
Catalog No. A25385

Gomisin N, a lignan compound derived from Schisandra chinensis, functions primarily as an apoptosis inducer. It has demonstrated the ability to activate key signaling pathways such as AMPK, Akt, MAPK/ERK, and Nrf2, while also promoting the activation of caspase-3 and PARP-1. Gomisin N exhibits a range of biological activities including anti-inflammatory, antioxidant, anti-obesity, anti-diabetic, and anti-melanogenesis effects, and has shown potential in inhibiting proinflammatory cytokines. Additionally, it possesses anti-tumor properties, particularly against cervical and liver cancers, and may offer benefits in the context of Alzheimer’s disease research.
Chemical Information
| Catalog Num | A25385 |
|---|---|
| M. Wt | 400.46 |
| Formula | C23H28O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 69176-52-9 |
| Synonyms | |
| SMILES | COC1=C2OCOC2=CC(C[C@@H]3C)=C1C(C(C[C@H]3C)=CC(OC)=C4OC)=C4OC |
Biological Activity
| Description | Gomisin N, a lignan compound derived from Schisandra chinensis, functions primarily as an apoptosis inducer. It has demonstrated the ability to activate key signaling pathways such as AMPK, Akt, MAPK/ERK, and Nrf2, while also promoting the activation of caspase-3 and PARP-1. Gomisin N exhibits a range of biological activities including anti-inflammatory, antioxidant, anti-obesity, anti-diabetic, and anti-melanogenesis effects, and has shown potential in inhibiting proinflammatory cytokines. Additionally, it possesses anti-tumor properties, particularly against cervical and liver cancers, and may offer benefits in the context of Alzheimer’s disease research. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


