Product Data Sheet
2'-Deoxyadenosine monohydrate-1′-13C
Catalog No. A25404
2'-Deoxyadenosine monohydrate-1′-13C is a stable isotope-labeled version of 2'-Deoxyadenosine monohydrate that primarily targets nucleotide metabolism. This compound exhibits significant biological activity by inhibiting glucose-stimulated insulin release and decreasing cyclic AMP (cAMP) accumulation in pancreatic islets. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH), thereby impacting cell growth. Its potential anticancer properties have been observed in colon cancer research, making it a valuable tool for investigations into nucleotide signaling and cancer biology.
Chemical Information
| Catalog Num | A25404 |
|---|---|
| M. Wt | 270.25 |
| Formula | C913CH15N5O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 446276-63-7 |
| Synonyms | |
| SMILES | OC[C@@H]1[C@@H](O)C[13C@H](N2C(N=CN=C3N)=C3N=C2)O1.O |
Biological Activity
| Description | 2'-Deoxyadenosine monohydrate-1′-13C is a stable isotope-labeled version of 2'-Deoxyadenosine monohydrate that primarily targets nucleotide metabolism. This compound exhibits significant biological activity by inhibiting glucose-stimulated insulin release and decreasing cyclic AMP (cAMP) accumulation in pancreatic islets. Additionally, it activates caspase-3, promoting apoptotic processes, and inhibits S-adenosyl-L-homocysteine hydrolase (SAHH), thereby impacting cell growth. Its potential anticancer properties have been observed in colon cancer research, making it a valuable tool for investigations into nucleotide signaling and cancer biology. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
