Product Data Sheet
Ac-DNLD-CHO
Catalog No. A25408
Ac-DNLD-CHO is a potent inhibitor of Caspase-3 and Caspase-7, exhibiting IC50 values of 9.89 nM and 245 nM, respectively, with corresponding Kiapp values of 0.68 nM and 55.7 nM. This reagent is valuable for investigating the role of caspase enzymes in apoptotic pathways and is particularly relevant in the study of diseases characterized by caspase-mediated cell death, including neurodegenerative disorders and viral infections. Researchers can utilize Ac-DNLD-CHO to explore therapeutic approaches targeting apoptosis in various health conditions.
Chemical Information
| Catalog Num | A25408 |
|---|---|
| M. Wt | 501.49 |
| Formula | C20H31N5O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 775289-20-8 |
| Synonyms | Ac-Asp-Asn-Leu-Asp-CHO |
| SMILES | [C@H](C(N[C@H](C(N[C@@H](CC(O)=O)C=O)=O)CC(C)C)=O)(NC([C@H](CC(O)=O)NC(C)=O)=O)CC(N)=O |
Biological Activity
| Description | Ac-DNLD-CHO is a potent inhibitor of Caspase-3 and Caspase-7, exhibiting IC50 values of 9.89 nM and 245 nM, respectively, with corresponding Kiapp values of 0.68 nM and 55.7 nM. This reagent is valuable for investigating the role of caspase enzymes in apoptotic pathways and is particularly relevant in the study of diseases characterized by caspase-mediated cell death, including neurodegenerative disorders and viral infections. Researchers can utilize Ac-DNLD-CHO to explore therapeutic approaches targeting apoptosis in various health conditions. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
