Product Data Sheet
Tauroursodeoxycholate-d4 sodium
Catalog No. A25440
Tauroursodeoxycholate-d4 sodium is a deuterium-labeled derivative of Tauroursodeoxycholic acid (TUDCA), serving as a stable isotope for research purposes. Primarily functioning as an endoplasmic reticulum (ER) stress inhibitor, Tauroursodeoxycholate demonstrates the ability to significantly reduce the expression of pro-apoptotic molecules, including caspase-3 and caspase-12, thereby mitigating ER stress-related apoptosis. Additionally, it has been shown to inhibit extracellular signal-regulated kinase (ERK) activity, making it valuable for studies investigating cellular stress responses and related pathways.
Chemical Information
| Catalog Num | A25440 |
|---|---|
| M. Wt | 525.71 |
| Formula | C26H40D4NNaO6S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2410279-95-5 |
| Synonyms | Tauroursodeoxycholic acid-d4 sodium; TUDCA-d4 sodium; UR 906-d4 sodium |
| SMILES | C[C@H](CCC(NCCS(=O)(O[Na])=O)=O)[C@H]1CC[C@@]2([H])[C@]3([H])[C@@H](O)C[C@]4([H])C([2H])([2H])[C@H](O)C([2H])([2H])C[C@]4(C)[C@@]3([H])CC[C@]12C |
Biological Activity
| Description | Tauroursodeoxycholate-d4 sodium is a deuterium-labeled derivative of Tauroursodeoxycholic acid (TUDCA), serving as a stable isotope for research purposes. Primarily functioning as an endoplasmic reticulum (ER) stress inhibitor, Tauroursodeoxycholate demonstrates the ability to significantly reduce the expression of pro-apoptotic molecules, including caspase-3 and caspase-12, thereby mitigating ER stress-related apoptosis. Additionally, it has been shown to inhibit extracellular signal-regulated kinase (ERK) activity, making it valuable for studies investigating cellular stress responses and related pathways. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
