Product Data Sheet
Homoeriodictyol
Catalog No. A25505
Homoeriodictyol is a flavanone metabolite of Eriocitrin that exhibits a range of biological activities. It enhances synaptic-related protein expression via NCOA4-mediated ferritin autophagy and offers potential cognitive benefits by improving memory impairment in mice through inhibition of the NLRP3 inflammasome. Additionally, Homoeriodictyol protects human endothelial cells against oxidative stress by activating the Nrf2 pathway and preventing mitochondrial dysfunction. Its anticancer properties are demonstrated through the inhibition of survival and migration in androgen-resistant prostate cancer cells, as well as its ability to induce apoptosis and enhance reactive oxygen species activity. Moreover, Homoeriodictyol displays antinociceptive effects in vivo.
Chemical Information
| Catalog Num | A25505 |
|---|---|
| M. Wt | 302.28 |
| Formula | C16H14O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 446-71-9 |
| Synonyms | |
| SMILES | O=C1C[C@@H](C2=CC=C(O)C(OC)=C2)OC3=CC(O)=CC(O)=C13 |
Biological Activity
| Description | Homoeriodictyol is a flavanone metabolite of Eriocitrin that exhibits a range of biological activities. It enhances synaptic-related protein expression via NCOA4-mediated ferritin autophagy and offers potential cognitive benefits by improving memory impairment in mice through inhibition of the NLRP3 inflammasome. Additionally, Homoeriodictyol protects human endothelial cells against oxidative stress by activating the Nrf2 pathway and preventing mitochondrial dysfunction. Its anticancer properties are demonstrated through the inhibition of survival and migration in androgen-resistant prostate cancer cells, as well as its ability to induce apoptosis and enhance reactive oxygen species activity. Moreover, Homoeriodictyol displays antinociceptive effects in vivo. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
