Product Data Sheet
Patrinoside aglucone
Catalog No. A25518
Patrinoside aglucone is an iridoid glucoside isolated from Valeriana tuberosa, exhibiting significant anticancer properties through G2/M phase tumor cell cycle arrest and apoptosis induction. This compound effectively inhibits the proliferation of cancer stem cells, such as MDA-MB-231 and U-251MG. Additionally, Patrinoside aglucone demonstrates potent anti-inflammatory activity, as evidenced by its ability to inhibit nitric oxide release (IC50: 43.44 μM) and reduce levels of pro-inflammatory cytokines including TNF-α, IL-1β, IL-6, PGE2, and COX-2.
Chemical Information
| Catalog Num | A25518 |
|---|---|
| M. Wt | 300.35 |
| Formula | C15H24O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 76319-15-8 |
| Synonyms | Patrinoside aglycone |
| SMILES | CC(C)CC(O[C@H]1[C@@]2([H])[C@@](C[C@@H]([C@@H]2CO)O)([H])C(CO)=CO1)=O |
Biological Activity
| Description | Patrinoside aglucone is an iridoid glucoside isolated from Valeriana tuberosa, exhibiting significant anticancer properties through G2/M phase tumor cell cycle arrest and apoptosis induction. This compound effectively inhibits the proliferation of cancer stem cells, such as MDA-MB-231 and U-251MG. Additionally, Patrinoside aglucone demonstrates potent anti-inflammatory activity, as evidenced by its ability to inhibit nitric oxide release (IC50: 43.44 μM) and reduce levels of pro-inflammatory cytokines including TNF-α, IL-1β, IL-6, PGE2, and COX-2. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
