Product Data Sheet
Tianeptine-d12
Catalog No. A25602
Tianeptine-d12 is a deuterated analog of Tianeptine, functioning as a stable isotope for research applications. Tianeptine is classified as an atypical antidepressant, acting primarily as a moderate-intensity agonist of the μ-opioid receptor and showing lesser activity at the δ-opioid receptor. This compound modulates glutamate signaling by enhancing AMPA receptor activity while antagonizing NMDA receptors, contributing to its neuroprotective effects under stress and inflammation. Additionally, Tianeptine exhibits anti-inflammatory and antioxidant properties and has been shown to inhibit MMP-9 through the suppression of the PI3K/Akt-mediated NF-κB pathway, making it relevant for studies in depression, anxiety, and neuroprotection.
Chemical Information
| Catalog Num | A25602 |
|---|---|
| M. Wt | 449.03 |
| Formula | C21H13D12ClN2O4S |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 1189870-26-5 |
| Synonyms | |
| SMILES | N(C(C(C(C(C(C(C(O)=O)([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])([2H])[2H])C1C=2C(S(=O)(=O)N(C)C=3C1=CC=CC3)=CC(Cl)=CC2 |
Biological Activity
| Description | Tianeptine-d12 is a deuterated analog of Tianeptine, functioning as a stable isotope for research applications. Tianeptine is classified as an atypical antidepressant, acting primarily as a moderate-intensity agonist of the μ-opioid receptor and showing lesser activity at the δ-opioid receptor. This compound modulates glutamate signaling by enhancing AMPA receptor activity while antagonizing NMDA receptors, contributing to its neuroprotective effects under stress and inflammation. Additionally, Tianeptine exhibits anti-inflammatory and antioxidant properties and has been shown to inhibit MMP-9 through the suppression of the PI3K/Akt-mediated NF-κB pathway, making it relevant for studies in depression, anxiety, and neuroprotection. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
