Phosphocreatine dipotassium
Catalog No. A25627

Phosphocreatine dipotassium is an endogenous metabolite that serves as a critical energy reservoir in vertebrate skeletal muscles. It enhances antioxidant activity and activates the TAK1 pathway, providing cardioprotective effects. Furthermore, phosphocreatine normalizes mitochondrial function and mitigates oxidative stress via the Akt-mediated Nrf2/HO-1 pathway. It also offers renal protection by suppressing apoptosis and reactive oxygen species generation through the ERK-mediated Nrf2/HO-1 pathway, making it a valuable reagent for studies in cellular metabolism and oxidative stress.
Chemical Information
| Catalog Num | A25627 |
|---|---|
| M. Wt | 287.29 |
| Formula | C4H8K2N3O5P |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 18838-38-5 |
| Synonyms | Creatine phosphate dipotassium; Creatinephosphoric acid dipotassium |
| SMILES | OC(CN(C(NP(O[K])(O[K])=O)=N)C)=O |
Biological Activity
| Description | Phosphocreatine dipotassium is an endogenous metabolite that serves as a critical energy reservoir in vertebrate skeletal muscles. It enhances antioxidant activity and activates the TAK1 pathway, providing cardioprotective effects. Furthermore, phosphocreatine normalizes mitochondrial function and mitigates oxidative stress via the Akt-mediated Nrf2/HO-1 pathway. It also offers renal protection by suppressing apoptosis and reactive oxygen species generation through the ERK-mediated Nrf2/HO-1 pathway, making it a valuable reagent for studies in cellular metabolism and oxidative stress. |
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Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.


