Product Data Sheet

Akt3 ligand-1

Catalog No. A25655

main product photo
Akt3 ligand-1 is a potent inhibitor of Akt3, exhibiting an IC50 of 0.1 nM. This compound serves as a ligand for the development of PROTAC strategies targeting Akt3, facilitating targeted protein degradation. Akt3 ligand-1 is invaluable for research into cancer biology and cellular signaling pathways where Akt3 plays a pivotal role. Additionally, it can be utilized to synthesize PROTAC Akt3 Degrader-1, enabling further exploration of therapeutic potentials in oncological studies.
Chemical Information
Catalog NumA25655
M. Wt440.93
FormulaC22H25ClN6O2
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.2794098-49-8
Synonyms
SMILESO=C1NC2=NC=NC(N3[C@H]4C[C@H]4N(CC3)C([C@@H](C5=CC=C(C=C5)Cl)CN)=O)=C2[C@@H](C1)C
Biological Activity
DescriptionAkt3 ligand-1 is a potent inhibitor of Akt3, exhibiting an IC50 of 0.1 nM. This compound serves as a ligand for the development of PROTAC strategies targeting Akt3, facilitating targeted protein degradation. Akt3 ligand-1 is invaluable for research into cancer biology and cellular signaling pathways where Akt3 plays a pivotal role. Additionally, it can be utilized to synthesize PROTAC Akt3 Degrader-1, enabling further exploration of therapeutic potentials in oncological studies.
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SHIPPING AND STORAGE
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