Product Data Sheet

Akt1-IN-4

Catalog No. A25666

main product photo
Akt1-IN-4 is a selective inhibitor of the AKT1-E17K mutant with an IC50 value of less than 15 nM. This compound effectively disrupts the activity of the AKT signaling pathway, which is implicated in various cancers. Akt1-IN-4 is suitable for research applications focused on studying the role of AKT1 mutations in tumorigenesis and therapeutic resistance.
Chemical Information
Catalog NumA25666
M. Wt621.69
FormulaC37H31N7O3
Purity>98%
Storageat -20 °C 3 years (powder form); at -20 °C 6 months (Solution base)
CAS No.3033577-05-5
Synonyms
SMILESNC1=C(C2=NC3=CC=C(C4=CC=CC=C4)N=C3N2C5=CC=C(CN6CC7(CN(C(C8=CC=C(O)C(C=O)=C8)=O)C7)C6)C=C5)C=CC=N1
Biological Activity
DescriptionAkt1-IN-4 is a selective inhibitor of the AKT1-E17K mutant with an IC50 value of less than 15 nM. This compound effectively disrupts the activity of the AKT signaling pathway, which is implicated in various cancers. Akt1-IN-4 is suitable for research applications focused on studying the role of AKT1 mutations in tumorigenesis and therapeutic resistance.
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