Product Data Sheet
N-Arachidonoyl-L-serine
Catalog No. A25732
N-Arachidonoyl-L-serine is an endocannabinoid that primarily targets Akt to induce phosphorylation in endothelial cells. It facilitates endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. Additionally, N-Arachidonoyl-L-serine demonstrates neuroprotective effects following traumatic brain injury by reducing apoptosis. It also promotes the opening of KV7.1/KCNE1 channels in mammalian cells, shortening action potential duration in cardiomyocytes. This compound is valuable for research in cardiovascular, cerebrovascular, and neurological disorders.
Chemical Information
| Catalog Num | A25732 |
|---|---|
| M. Wt | 391.54 |
| Formula | C23H37NO4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 187224-29-9 |
| Synonyms | ARA-S |
| SMILES | CCCCC/C=C\C/C=C\C/C=C\C/C=C\CCCC(N[C@H](C(O)=O)CO)=O |
Biological Activity
| Description | N-Arachidonoyl-L-serine is an endocannabinoid that primarily targets Akt to induce phosphorylation in endothelial cells. It facilitates endothelium-dependent vasodilation in isolated rat mesenteric and abdominal aortas. Additionally, N-Arachidonoyl-L-serine demonstrates neuroprotective effects following traumatic brain injury by reducing apoptosis. It also promotes the opening of KV7.1/KCNE1 channels in mammalian cells, shortening action potential duration in cardiomyocytes. This compound is valuable for research in cardiovascular, cerebrovascular, and neurological disorders. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
