Product Data Sheet
Etilefrine
Catalog No. A25855
Etilefrine is an α/β-adrenergic agonist primarily targeting α1 and β1 receptors. Its activity induces vasoconstriction by stimulating α1 receptors, leading to increased peripheral resistance, while β1 receptor activation enhances myocardial contractility and elevates heart rate, resulting in improved blood pressure and cardiac output. Additionally, Etilefrine modulates the AMPK/Akt signaling pathway, influencing phosphorylation levels. This compound is applicable in cardiovascular research, notably in studies related to postural hypotension, chylothorax, and conditions characterized by low cardiac output.
Chemical Information
| Catalog Num | A25855 |
|---|---|
| M. Wt | 181.23 |
| Formula | C10H15NO2 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 709-55-7 |
| Synonyms | |
| SMILES | OC(CNCC)C1=CC=CC(O)=C1 |
Biological Activity
| Description | Etilefrine is an α/β-adrenergic agonist primarily targeting α1 and β1 receptors. Its activity induces vasoconstriction by stimulating α1 receptors, leading to increased peripheral resistance, while β1 receptor activation enhances myocardial contractility and elevates heart rate, resulting in improved blood pressure and cardiac output. Additionally, Etilefrine modulates the AMPK/Akt signaling pathway, influencing phosphorylation levels. This compound is applicable in cardiovascular research, notably in studies related to postural hypotension, chylothorax, and conditions characterized by low cardiac output. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
