Product Data Sheet
Akt3 degrader 1
Catalog No. A25861
Akt3 degrader 1 is a selective degrader that targets Akt3, effectively overcoming Osimertinib-induced resistance in H1975OR non-small cell lung cancer (NSCLC) cells. This compound demonstrates anti-proliferative effects and significantly inhibits tumor growth in murine models. Akt3 degrader 1 is a valuable tool for investigating mechanisms of drug resistance in NSCLC and can facilitate the development of novel therapeutic strategies.
Chemical Information
| Catalog Num | A25861 |
|---|---|
| M. Wt | 885.19 |
| Formula | C53H72N8O4 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 2836342-69-7 |
| Synonyms | |
| SMILES | COC1=C(C=CC(N2CCN(CC2)CCCCCCCCCCCCNC(CC34CC5CC(C4)CC(C3)C5)=O)=C1)NC6=NC=C7C(C)=CC(N(C7=N6)C8=CC=CC(NC(C9CC9)=O)=C8)=O |
Biological Activity
| Description | Akt3 degrader 1 is a selective degrader that targets Akt3, effectively overcoming Osimertinib-induced resistance in H1975OR non-small cell lung cancer (NSCLC) cells. This compound demonstrates anti-proliferative effects and significantly inhibits tumor growth in murine models. Akt3 degrader 1 is a valuable tool for investigating mechanisms of drug resistance in NSCLC and can facilitate the development of novel therapeutic strategies. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
