Product Data Sheet
(+)-Medioresinol
Catalog No. A25864
(+)-Medioresinol is a furofuran-type lignan that exhibits notable antifungal and antibacterial activities. It enhances the efficacy of antibiotics through its antimicrobial and antibiofilm properties and promotes intracellular reactive oxygen species (ROS) accumulation, leading to mitochondrial-mediated apoptosis in Candida albicans. Additionally, (+)-Medioresinol inhibits LPS-stimulated IL-12p40 production and acts as a PGC-1α activator, providing protection against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. This compound is valuable for research into fungal and bacterial infections, inflammatory responses, and ischemic stroke mechanisms.
Chemical Information
| Catalog Num | A25864 |
|---|---|
| M. Wt | 388.41 |
| Formula | C21H24O7 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 40957-99-1 |
| Synonyms | |
| SMILES | COC1=C(O)C(OC)=CC([C@]2([H])[C@]3([H])[C@@](CO2)([H])[C@](C4=CC(OC)=C(C=C4)O)([H])OC3)=C1 |
Biological Activity
| Description | (+)-Medioresinol is a furofuran-type lignan that exhibits notable antifungal and antibacterial activities. It enhances the efficacy of antibiotics through its antimicrobial and antibiofilm properties and promotes intracellular reactive oxygen species (ROS) accumulation, leading to mitochondrial-mediated apoptosis in Candida albicans. Additionally, (+)-Medioresinol inhibits LPS-stimulated IL-12p40 production and acts as a PGC-1α activator, providing protection against endothelial cell pyroptosis in ischemic stroke via the PPARα-GOT1 axis. This compound is valuable for research into fungal and bacterial infections, inflammatory responses, and ischemic stroke mechanisms. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
