Product Data Sheet
Auriculasin
Catalog No. A25873
Auriculasin is an anticancer agent that primarily targets VEGFR2, PI3K/AKT/mTOR, and MAPK signaling pathways. It effectively inhibits cell proliferation, induces apoptosis, and suppresses angiogenesis, while also promoting mitochondrial oxidative stress and ferroptosis. Additionally, Auriculasin demonstrates activity at the cannabinoid receptor CB1 with an IC50 of 8.92 μM. This compound is valuable for cancer research, particularly in studying prostate cancer, non-small cell lung cancer, and the development of anti-angiogenic therapies.
Chemical Information
| Catalog Num | A25873 |
|---|---|
| M. Wt | 420.45 |
| Formula | C25H24O6 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 60297-37-2 |
| Synonyms | |
| SMILES | O=C1C(C(O)=C(C=CC(C)(C)O2)C2=C3C/C=C(C)\C)=C3OC=C1C4=CC=C(O)C(O)=C4 |
Biological Activity
| Description | Auriculasin is an anticancer agent that primarily targets VEGFR2, PI3K/AKT/mTOR, and MAPK signaling pathways. It effectively inhibits cell proliferation, induces apoptosis, and suppresses angiogenesis, while also promoting mitochondrial oxidative stress and ferroptosis. Additionally, Auriculasin demonstrates activity at the cannabinoid receptor CB1 with an IC50 of 8.92 μM. This compound is valuable for cancer research, particularly in studying prostate cancer, non-small cell lung cancer, and the development of anti-angiogenic therapies. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
