Product Data Sheet
Rhodiolin
Catalog No. A25890
Rhodiolin is a flavonoid that acts as a GPI (glucose 6-phosphate isomerase) and NS2B-NS3 protease inhibitor, with significant implications for cancer and viral research. It demonstrates the ability to inhibit glycolysis in papillary thyroid cancer, leading to suppressed PI3K/AKT/mTOR signaling and induced apoptosis. Additionally, Rhodiolin disrupts dengue viral replication through its action on the NS2B-NS3 protease. With its potential to inhibit CK1ε kinase, it serves as a valuable candidate for developing anticancer strategies and investigating anti-tumor and antiviral mechanisms.
Chemical Information
| Catalog Num | A25890 |
|---|---|
| M. Wt | 480.42 |
| Formula | C25H20O10 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 86831-53-0 |
| Synonyms | |
| SMILES | O=C1C2=C(O)C=C(O[C@H](C3=CC(OC)=C(O)C=C3)[C@@H](CO)O4)C4=C2OC(C5=CC=C(O)C=C5)=C1O |
Biological Activity
| Description | Rhodiolin is a flavonoid that acts as a GPI (glucose 6-phosphate isomerase) and NS2B-NS3 protease inhibitor, with significant implications for cancer and viral research. It demonstrates the ability to inhibit glycolysis in papillary thyroid cancer, leading to suppressed PI3K/AKT/mTOR signaling and induced apoptosis. Additionally, Rhodiolin disrupts dengue viral replication through its action on the NS2B-NS3 protease. With its potential to inhibit CK1ε kinase, it serves as a valuable candidate for developing anticancer strategies and investigating anti-tumor and antiviral mechanisms. |
|---|
RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
