Product Data Sheet
3,4,5-Tricaffeoylquinic acid
Catalog No. A25900
3,4,5-Tricaffeoylquinic acid is an NF-κB inhibitor known for its ability to suppress tumor necrosis factor-α-induced inflammatory mediators in keratinocytes through the inhibition of Akt and NF-κB signaling pathways. This compound also induces cell cycle arrest at the G0/G1 phase, facilitates actin cytoskeleton organization, and promotes chromatin remodeling and neuronal differentiation in human neural stem cells. Additionally, 3,4,5-Tricaffeoylquinic acid is valuable for research into aging-associated diseases.
Chemical Information
| Catalog Num | A25900 |
|---|---|
| M. Wt | 678.59 |
| Formula | C34H30O15 |
| Purity | >98% |
| Storage | at -20 °C 3 years (powder form); at -20 °C 6 months (Solution base) |
| CAS No. | 86632-03-3 |
| Synonyms | 3,4,5-triCQA |
| SMILES | O=C([C@]1(O)C[C@@H](OC(/C=C/C2=CC=C(O)C(O)=C2)=O)[C@@H](OC(/C=C/C3=CC=C(O)C(O)=C3)=O)[C@H](OC(/C=C/C4=CC=C(O)C(O)=C4)=O)C1)O |
Biological Activity
| Description | 3,4,5-Tricaffeoylquinic acid is an NF-κB inhibitor known for its ability to suppress tumor necrosis factor-α-induced inflammatory mediators in keratinocytes through the inhibition of Akt and NF-κB signaling pathways. This compound also induces cell cycle arrest at the G0/G1 phase, facilitates actin cytoskeleton organization, and promotes chromatin remodeling and neuronal differentiation in human neural stem cells. Additionally, 3,4,5-Tricaffeoylquinic acid is valuable for research into aging-associated diseases. |
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RETURN POLICY
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
Adooq’s Unconditional Return Policy ensures a smooth online shopping experience for our customers. If you are in any way unsatisfied with your purchase, you may return any item(s) within 7 days of receiving it. In the event of product quality issues, either protocol related or product related problems, you may return any item(s) within 365 days from the original purchase date. Please follow the instructions below when returning products.
SHIPPING AND STORAGE
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
Adooq products are transported at room temperature. If you receive the product at room temperature, please rest assured, the Adooq Quality Inspection Department has conducted experiments to verify that the normal temperature placement of one month will not affect the biological activity of powder products. After collecting, please store the product according to the requirements described in the datasheet. Most Adooq products are stable under the recommended conditions.
